Birgül Varan, M.D

Pediatric Cardiology

Birgül Varan, M.D

Pediatric Cardiology


+90 0312 203 68 68 / 4863




     

Education    
1983-1989 Hacettepe University Faculty of Medicine (English)
1989-1994  Hacettepe University Faculty of Medicine, Department of Pediatrics

1998-2002  Baskent University Faculty of Medicine Pediatric Cardiology Unit

Medical Field of Expertise 
Echocardiography

Interventional Cardiac Catheterization

Fetal Echocardiography

Work Experience
1994-1998  Baskent University Faculty of Medicine Department of Pediatrics

2002-           Baskent University Faculty of Medicine Pediatric Cardiology Unit


Professional Memberships 
Turkish Pediatric Cardiology and Cardiovascular Surgery Association

Adult Congenital Heart Disease Association

Turkish Transplantation Society

Researches and Publications
International Journal Papers: 76
National Journal Papers: 10


Presentation/Posters
International Conference Proceeding : 24
National Conference Proceeding: 35

Meetings

National Pediatric Cardiology and Cardiovascular Surgery Congress
World Congress of Pediatric Cardiology
European Association of Pediatric Cardiology Congress

Interventional Pediatric Cardiology Congress

Fetal Doppler Meeting

 

International Publications:

1-            Ceyhan M, Kanra G, Benderlioğlu B, Seçmeer G, Hiçsönmez G, Kirazlı Ş. Transient Protein S  deficiency with deep venous thrombosis during Salmonella typhimirium infection. Arch Dis Child 1993;68:138-9                        

2-            Varan B, Saatçi Ü, Özen S, Bakkaloğlu A, Beşbaş N. Efficacy of oxybutynin, pseudoephedrine and indomethacin in the treatment of primary nocturnal enuresis. Turk J Pediatr 1996;38:155-59

3-            Varan B, Karakayalı H, Kutsal A, Özdemir N. Spontaneous hemothorax in a hemodialysis patient. Pediatr Nephrol 1998; 12:65-6    

4-            Haberal  M, Bilgin N, Arslan G, Harakayalı H, Akpınar E, Moray G, Varan B, Turan M,  Boyacıoğlu S. Living-related donor liver transplantation. Transplant Proc 1998; 30: 2267-2268

5-            Varan B, Tokel K, Yılmaz G. Malnutrition and growth failure in cyanotic and acyanotic congenital heart disease with and without pulmonary hypertension. Arch Dis Child 1999;81: 49-52

6-            Varan B, Gürakan B, Özbek N, Emir S. Subcutaneous fat necrosis of the newborn associated with anemia.  Pediatr Dermatol 1999; 16: 381-383       

7-            Gürakan B, Özbek N, Varan B, Demirhan B. Fatal acidosis in a neonate with Pearson syndrome. Turk J Pediatr 1999; 41: 361-364

8-            Yılmaz G, Varan B, Gürakan B, Yılmaz T. Intranasal budesonide spray as an adjunct to oral antibiotic therapy for acute sinusitis in children. Eur Arch Otorhinolaryngol 2000; 257:256-259

9-            Mercan S, Sezgin A, Gültekin B, Tokel K, Saygılı A, Varan B, Aşlamacı S. Xenograft and homograft transplantation in cardiac surgery at Başkent University Hospital. Transplant Proc 2000; 32: 594-595

10-         Emir S, Bereket G, Boyacıoğlu S, Varan B, Tunalı H, Haberal M. Gastroduodenal lesions and Helicobacter pylori in children with end-stage renal disease. Pediatric Nephrol 2000; 14: 837-840

11-         Topaloğlu R, Kiper N, Göçmen A, Varan B, Saatçi Ü. Pulmonary hemosiderosis with juvenile rheumatoid arthritis: a case report. Turk J Pediatr 2000; 42: 148-150     

12-         Varan A, Doğancı T, Taşkın M, Üner A, Varan B.  Gastrointestinal autonomic nerve tumor: the youngest case reported in the literature. J Pediatr Gastroenterol Nutr 2000; 31: 183-184 (Science Citation Index)                       

13-         Tokel K, Boyvat F, Varan B. Coil embolization of pulmonary sequestration in two infants : A safe alternative to surgery. Am J Roentgenol 2000; 175: 993-995

14-         Dönmez A, Kızılkan A, Berksun H, Varan B, Tokel K. One center's experience with remifentanil infusion in pediatric cardiac catheterization. J Cardiothoracic Vasc Anesthesia 2001; 15: 736-739

15-         Akman A, Varan B, Akova YA, Aydın P. Ocular involvement in siblings with Familial Mediterrenean Fever. J Pediatr Ophthalmol Strabismus 2001; 38: 114-116 

16-         Arda IS, Ergin F, Varan B, Demirhan B, Aslan H, Özyaylalı İ. Acute abdomen caused by Salmonella typhimurium infection in children. J Pediatr Surg  2001; 36: 1849-1852

17-         Varan B, Atalay H, Cemil T, Saygılı A, Mercan Ş, Tokel K. Bilateral adrenal calcification associated with congenital heart disease. South Med J 2002; 95: 784-785

18-         Tokel K, Varan B, Mercan S, Saygılı A, Tarcan A, Gürakan B. Multiorgan failure due to coarctation of the aorta.: Management and outcome in five neonates. Pediatr   Emergency Care  2002; 18: E8-10

19-         Varan B, Tokel K, Mercan Ş, Dönmez A, Aşlamacı S. Systemic inflammatory response syndrome related to cardiopulmonary bypass and its modification by methyl prednisolone: High-dose versus low-dose. Pediatr Cardiol 2002; 23: 437-441

20-         Özçay F, Tokel K, Varan B, Saygılı A. Cardiac evaluation of pediatric liver transplantation candidates. Transplant Proc 2002; 34: 2150-2152

21-         Özçay F, Gür G, Varan B, Demirhan B, Boyacıoğlu S. Evaluation of potential donors for living related pediatric liver transplantation. Transplant Proc 2002; 34: 2148-2149

22-         Derbent M, Yılmaz Z, Baltacı V, Saygılı A, Varan B, Tokel K. Chromosome 22q11.2 deletion and phenotypic features in 30 patients with conotruncal heart defects. Am J Med Genetics 2003; 116A:  129-135             

23-         Pirat A, Karaaslan P, Candan S, Zeyneloğlu P, Varan B, Tokel K, Torgay A, Arslan G. Topical EMLA cream versus prilocaine infiltration for pediatric cardiac catheterization. J Cardiothorac and Vasc Anesthesia 2005; 19: 642-645

24-         Derbent M, Örün UA, Varan B, Mercan Ş, Yılmaz Z, Şahin FI, Tokel K. A new syndrome within the oculo-auriculo-vertebral spectrum: microtia, atresia of the external auditory canal, vertebral anomaly, and complex cardiac defects. Clin Dysmorphol 2005; 14: 27-30 

25-         Yıldırım SV, Azak E, Varan B, Tokel K. Unusual and early hyperglycemia following amiodarone infusion in two infants. Pediatr Cardiol 2005; 26: 715-716            

26-         Çetin İİ, Örün UA, Varan B, Coşkun M, Tokel K. A case of aortopulmonary window simulating common arterial trunk presented at the age of 13. Cardiovasc Intervent Radiol              2005; 28: 533-535

27-         Akay TH, Özkan S, Gültekin B, Uguz E, Varan B, Sezgin A, Tokel K, Aşlamacı S. Diaphragmatic paralysis after cardiac surgery in children: incidence, prognosis and surgical management. Pediatr Surg Int. 2006; 22: 341-346

28-         Kınık ST, Varan B, Yıldırım ST, Tokel K. The effect of obesity on echocardiographic and metabolic parameters in childhood. J Pediatr Endocrinol Metab. 2006;19:1007-1014

29-         Erol I, Çetin İİ, Alehan F, Varan B, Özkan S, Ağıldere M, Tokel K. Brain abscess   associated with isolated left superior vena cava draining into the left atrium in the absence of coronary sinus and atrial septal defect. Cardiovasc Intervent Radiol 2006;29: 454-456

30-         Eroğlu D, Yanık F, Sakallıoğlu AE, Arıkan U, Varan B, Kuşçu E. Prenatal diagnosis of bilateral diaphragmatic hernia by fetal sonography. J Obstet Gynaecol Res. 2006;32: 90-93.

31-         Özçay F, Varan B,Tokel K, Çetin İ, Dalgıç A, Haberal M. Severe peripheral pulmonary artery stenosis is not a contraindication to liver transplantation in Alagille syndrome. Pediatr Transplant. 2006;10:108-111

32-         Kınık ST, Özçay F, Varan B. Type I diabetes mellitus, Hashimoto's thyroiditis and celiac disease in an adolescent with Down syndrome. Pediatr Int 2006; 48: 433-435

33-         Alioğlu B, Demirhan B, Özyürek E, Varan B, Erbay A, Özbek N. Pulmonary hypertension              in a child with juvenile myelomonocytic leukemia secondary to pulmonary leukemic cell infiltration. Pediatr Hematol Oncol. 2006; 23: 667-675

34-         Yıldırım SV, Tokel K, Varan B, Aşlamacı S, Ekici E. Clinical investigations over 13 years to establish the nature of the cardiac defects in patients having abnormalities of lateralization. Cardiol Young. 2007;17: 275-282

35-         Çetin I, Tokel K, Varan B, Orun UA, Gokdemir M, Cindik N, Eyüboğlu F, Ulubay G, Aşlamaci S. Evaluation of right ventricular functions and B-type natriuretic peptide levels by cardiopulmonary exercise test in patients with pulmonary regurgitation after repair of tetralogy of Fallot. J Card Surg 2008; 23: 493-498

36-         Çetin I, Bikmaz YE, Varan B. A case of rheumatic fever with multiple recurrences of carditis. Turk J Pediatr 2008; 50:186-188

37-         Onay OS, Kinik ST, Otgün Y, Arda IS, Varan B. Jarcho-Levin syndrome presenting with diaphragmatic hernia. Eur J Pediatr Surg 2008; 18: 272-4

38-         Yildirim SV, Kervancioğlu M, Varan B, Tokel K. Congenital pulmonary venous stenosis combined with valvular aortic stenosis: a very rare case. Congen Heart Dis 2008; 3: 223-225

39-         Derbent M, Anuk D, Tarcan A,  Varan B, Gurakan B, Tokel K. Functional pulmonary atresia in a patient with neonatal Marfan syndrome caused by a c.3602G>A mutation in exon 29 of  the FBN1 gene. Clin Dysmorphol 2008; 17: 127-128

40-   Akpek EA, Pirat A, Varan B, Mercan S. Malposition of subclavian vein catheter due to    undiagnosed persistant superior vena cava during pediatric cardiac surgery. Paediatr Anaesth 2008; 18: 1265-7

41-         Yildirim SV, Tokel K, Saygili B, Varan B. The incidence and risk factors of arrhythmias in the early period after cardiac surgery in pediatric patients. Turk J Pediatr. 2008 Nov-Dec;50(6):549-53.

42-         Çetin I, Varan B, Orun UA, Tokel K. Common trunks of the subclavian and the vertebral arteries: Presentation of a new aortic arch anomaly. Ann Vasc Surg 2009; 23: 142-143 

43-         Ekici F, Varan B, Saylan-Cevik B, Ozkan M, Ok-Atilgan A, Oktay A. A large intracardiac fungus ball in a premature infant. Turk J Pediatr. 2011 May-Jun;53(3):325-7.

44-         Kervancioglu M, Tokel K, Varan B, Yildirim SV.Frequency, origins and courses of anomalous coronary arteries in 607 Turkish children with tetralogy of Fallot. Cardiol J. 2011;18(5):546-51.

45-         Erbay A, Sarialioglu F, Malbora B, Yildirim SV, Varan B, Tarcan A, Gülcan H, Demir S, Derbent M, Uslu N, Abbasoğlu A. Propranolol for infantile hemangiomas: a preliminary report on efficacy and safety in very low birth weight infants. Turk J Pediatr. 2010 Sep-Oct;52(5):450-6.

46-         Karagöl BS, Tokel K, Varan B, Mercan S. The incidence of thrombocytopenia after cardiopulmonary bypass in children with Down syndrome. Turk Kardiyol Dern Ars. 2011 Jun;39(4):283-91.

47-         Yıldırır A, Varan B, Erdoğan I, Boyvat F. Case images: percutaneous retrieval of an embolized occluder device from the aorta using a goose-neck snare. Turk Kardiyol Dern Ars. 2012 Jun;40(4):393

48-         Ince DA, Ecevit A, Kurt A, Varan B, Tarcan A. Dicephalic parapagus conjoined twins. Indian J Pediatr. 2012 Jun;79(6):818-9.

49-         Saygı S, Olgaç A, Üçkardeş Y, Alehan F, Varan B. Acute disseminated encephalomyelitis associated with acute rheumatic fever. Pediatr Neurol. 2011 Mar;44(3):233-5.

50-         Derbent M, Öncel Y, Tokel K, Varan B, Haberal A, Yazici AC, Legius E, Özbek N. Clinical and hematologic findings in Noonan syndrome patients with PTPN11 gene mutations. Am J Med Genet A. 2010 Nov;152A(11):2768-74.

51-         Baskin E, Gulleroglu KS, Saygili A, Aslamaci S, Varan B, Tokel K. Peritoneal dialysis requirements following open-heart surgery in children with congenital heart disease. Ren Fail. 2010;32(7):784-7.

52-         Tokel K, Azak E, Ayabakan C, Varan B, Aşlamaci SA, Mercan S. Somatic growth after corrective surgery for congenital heart disease. Turk J Pediatr. 2010 Jan-Feb;52(1):58-67.

53-         Cindik N, Ozcay F, Süren D, Akkoyun I, Gökdemir M, Varan B, Alehan F, Ozbek N, Tokel K. Gaucher disease with communicating hydrocephalus and cardiac involvement. Clin Cardiol. 2010 Jan;33(1):E26-30.

54-         Cetin I, Tokel K, Varan B, Orün U, Aşlamaci S. Evaluation of right ventricular function by using tissue Doppler imaging in patients after repair of tetralogy of fallot. Echocardiography. 2009 Sep;26(8):950-7.

55-         Cetin I, Ozkan S, Varan B, Gökdemir M, Ceviz N, Kantarci M, Tokel K. Anomalous pulmonary venous connection to the azygous vein: surgical approach of a case with 3D computed tomography findings. J Card Surg. 2009 May-Jun;24(3):345-7.

56-         Oncel MY, Yilmaz Z, Karadag Oncel E, Varan B, Gulleroglu KS, Baskin E, Derbent M. Dilated cardiomyopathy in a patient with 22q11.2 microdeletion syndrome. Genet Couns. 2013;24(2):235-8.

57-         Ekici F, Varan B, Kocabaş A, Erdoğan İ, Eminoğlu S, Aktaş D. Multiple giant aneurysms and stenoses of the coronary and systemic arteries in an infant with kawasaki disease at the early stage of convalescent period. Echocardiography. 2014 May;31(5):E147-50. doi: 10.1111/echo.12535. Epub 2014 Feb 14.

58-         Gürsu AH, Boyvat F, Varan B, Erdoğan I. Embolization of pulmonary sequestration with Onyx: an unusual application. Turk Kardiyol Dern Ars. 2014 Mar;42(2):174-7. doi: 10.5543/tkda.2014.09365.

59-         Dogan M, Firinci F, Balci YI, Zeybek S, Ozgürler F, Erdogan I, Varan B, Semerci CN. The Roberts syndrome: a case report of an infant with valvular aortic stenosis and mutation in ESCO2. J Pak Med Assoc. 2014 Apr;64(4):457-60.

60-         Gursu HA, Erdogan I, Varan B, Oktay A, Ozcay F, Ozkan M, Aslamaci S. Oral budesonide as a therapy for protein-losing enteropathy in children after the Fontan operation. J Card Surg. 2014 Sep;29(5):712-6. doi: 10.1111/jocs.12355. Epub 2014 Jun 3.

61-         Karataş Z, Karataş A, Özlü T, Goksugur SB, Varan B. Bicuspid aortic valve and severe aortic stenosis in a newborn exposed to carbamazapine during pregnancy. J Turk Ger Gynecol Assoc. 2014 Aug 8;15(4):259-61. doi: 10.5152/jtgga.2014.89577. eCollection 2014.

62-         Gursu HA, Varan B, Erdogan İ, Oktay A. Transposition of the great arteries and cor triatriatum: a rare combination. Cardiol Young. 2014 Aug;24(4):760-1

63-         Yazıcı N, Sarıalioğlu F, Varan B, Aşlamacı S, Tarhan C, Atılgan AO. Treatment of cardiac infantile fibrosarcoma. Pediatr Blood Cancer. 2013 Jun;60(6):953-4.

64-         Gürsu HA, Varan B, Oktay A, Özkan M. A case of neonatal arterial thrombosis mimicking interrupted aortic arch. Turk Pediatri Ars. 2015 Jun 1;50(2):118-22. doi: 10.5152/tpa.2015.869. eCollection 2015 Jun.

65-         Gürsu AH, Varan B, Özkan M. Case images: A rare variation in drainage of total anomalous pulmonary venous return. Turk Kardiyol Dern Ars. 2015 Oct;43(7):659.

66-         Gursu HA, Varan B, Sade E, Erdogan I, Ozkan M. Analysis of right ventricle function with strain imaging before and after pulmonary valve replacement. Cardiol J. 2016;23(2):195-201.

67-         Erdogan I, Varan B, Sezgin A, Pirat A, Zeyneloglu P. Rituximab Therapy for Rejection in Pediatric Heart Transplant. Exp Clin Transplant. 2018 Apr;16(2):199-203. doi: 10.6002/ect.2015.0370. Epub 2016 May 17.

68-         Gursu HA, Varan B, Sade E, Erdogan I, Sezgin A, Aslamaci S. Evaluation of Acute Rejection by Measuring Strain and Strain Rate in Children With Heart Transplant: A Preliminary Report. Exp Clin Transplant. 2017 Oct;15(5):561-566.

69-         Erdogan I, Gursu HA, Varan B, Ozkan M, Sezgin A. Hypomagnesemia in Pediatric Heart Transplant Patients Treated with Tacrolimus. Exp Clin Transplant. 2018 Oct;16(5):592-595.

70-         Yakut K, Erdoğan İ, Varan B, Atar İ. A Report of Brugada Syndrome Presenting with Cardiac Arrest Triggered by Verapamil Intoxication. Balkan Med J. 2017 Dec 1;34(6):576-579.

71-         Tokel K, Gümüş A, Ayabakan C, Varan B, Erdoğan İ. Complications of cardiac catheterization in children with congenital heart disease. Turk J Pediatr. 2018;60(6):675-683.

72-         Yakut K, Varan B, Ozkan M. A rare cause of cyanosis in newborns: arteriovenous fistula between the right pulmonary artery and the left atrium and its treatment. Cardiol Young. 2018 Apr;28(4):605-607.

73-         Yakut K, Tokel K, Varan B, Erdoğan İ, Özkan M.  [Case report and the surgical treatment of two cases with pulmonary atresia in which pulmonary arteries is circulated by coronary arteries]. Turk Kardiyol Dern Ars. 2018 Apr;46(3):216-220.

74-         Varan B, Yakut K, Harman A. Transcatheter retrieval of embolized catheter using venovenous loop in a neonate. Turk J Pediatr. 2018;60(1):113-115.

75-         Varan B, Yakut K, Tokel K, Özkan S, Aşlamacı S. A rare complication of balloon pulmonary angioplasty: Aortopulmonary window and its treatment. Anatol J Cardiol. 2019 Jan;21(1):46-47.

76-         Sahin-Uysal N, Gulumser C, Kocaman E, Varan B, Bayraktar N, Yanık F. Maternal and cord blood homocysteine, vitamin B12, folate, and B-type natriuretic peptide levels at term for predicting congenital heart disease of the neonate: A case-control study. J Matern Fetal Neonatal Med. 2019 Jul 1:1-8.