Prof. Dr. Göğşen Önalan

Kadın Hastalıkları ve Doğum Anabilim Dalı

Prof. Dr. Göğşen Önalan

Kadın Hastalıkları ve Doğum Anabilim Dalı

0 312 203 03 14-15


      1989 - 1994

Uzmanlık Eğitimi: Zekai Tahir Burak Eğitim ve Araştırma Hastanesi

      1983 - 1989

Tıp Eğitimi: Çukurova Üniversitesi Tıp Fakültesi




Başkent Üniversitesi Ankara Hastanesi


Uzmanlık Alanları


Kadın Hastalıkları ve Doğum

Reprodüktif Endokrinoloji ve İnfertilite


Bi̇li̇msel Yayınlar


A. Uluslararası hakemli dergilerde yayımlanan makaleler :

A1. Atasoy Karakas L, Esin S, Sahin Uysal N, Tohma YA, Onalan G, Zeyneloglu HB.

Granulocyte colony-stimulating factor in assisted reproductive technology

treatment does not increase the risk of adverse perinatal outcomes in twin

pregnancies. J Obstet Gynaecol. 2023 Dec;43(1):2186776. doi:

10.1080/01443615.2023.2186776. PMID: 36899463.


A2. Ayhan A, Tunç M, Atasoy Karakaş L, Tekelioğlu T, Haberal Reyhan AN, Önalan G,

Kuşçu E. Oncologic and obstetric outcomes of early-stage epithelial ovarian

cancer patients who underwent fertility-sparing surgery: A retrospective study.

Int J Gynaecol Obstet. 2023 Feb 24. doi: 10.1002/ijgo.14732. Epub ahead of

print. PMID: 36825554.


A3. Zeyneloglu HB, Tohma YA, Gunakan E, Abasıyanık MA, Sozen C, Onalan G. Diet

and pravastatin administration prior to <i>in vitro</i> fertilization treatment

may improve pregnancy outcome in women with dyslipidemia. J Obstet Gynaecol.

2022 Aug;42(6):2235-2240. doi: 10.1080/01443615.2022.2036968. Epub 2022 Mar 8.

PMID: 35257641.


A4. Zeyneloglu HB, Tohma YA, Gunakan E, Onalan G, Eryılmaz T. Dydrogesterone

primed luteal phase stimulation may be better than follicular phase stimulation

in patients with diminished ovarian reserve. Gynecol Endocrinol. 2021

Nov;37(11):1000-1002. doi: 10.1080/09513590.2021.1922885. Epub 2021 May 4. PMID:



A5. Balci S, Tohma YA, Esin S, Onalan G, Tekindal MA, Zeyneloglu HB. Gut

dysbiosis may be associated with hyperemesis gravidarum. J Matern Fetal Neonatal

Med. 2022 Jun;35(11):2041-2045. doi: 10.1080/14767058.2020.1777268. Epub 2020

Jun 10. PMID: 32519907.


A6. Tohma YA, Musabak U, Gunakan E, Akilli H, Onalan G, Zeyneloglu HB. The Role

of Analysis of NK Cell Subsets in Peripheral Blood and Uterine Lavage Samples in

Evaluation of Patients with Recurrent Implantation Failure. J Gynecol Obstet Hum

Reprod. 2020 Nov;49(9):101793. doi: 10.1016/j.jogoh.2020.101793. Epub 2020 May

13. PMID: 32413518.


A7. Uysal NŞ, Gülümser Ç, Bilgin Yanık FF, Önalan G, Zeyneloğlu HB. Outcome of

ICSI pregnancies with spontaneous loss of a co-twin compared with singleton ICSI

pregnancies: Single center experience. J Obstet Gynaecol Res. 2020

Mar;46(3):445-450. doi: 10.1111/jog.14177. Epub 2020 Jan 10. PMID: 31922328.


A8. Zeyneloglu HB, Tohma YA, Onalan G, Moran U. Granulocyte colony-stimulating

factor for intracytoplasmic sperm injection patients with repeated implantation

failure: which route is best?†. J Obstet Gynaecol. 2020 May;40(4):526-530. doi:

10.1080/01443615.2019.1631772. Epub 2019 Sep 9. PMID: 31496328.


A9. Tohma YA, Onalan G, Esin S, Sahin H, Aysun D, Kuscu E, Haberal A, Zeyneloglu

HB. Are There Any Predictors of Endometrial Premalignancy/Malignancy within

Endometrial Polyps in Infertile Patients? Gynecol Obstet Invest.

2019;84(5):512-518. doi: 10.1159/000501682. Epub 2019 Jul 16. PMID: 31311015.


A10. Tohma YA, Onalan G, Tepeoglu M, Bayraktar N, Colak E, Ozcimen EE, Zeyneloglu

HB. Phosphodiesterase 4 inhibitor plus metformin is superior to metformin alone

for the treatment of polycystic ovary syndrome: A rat model study. Exp Ther Med.

2019 May;17(5):4013-4022. doi: 10.3892/etm.2019.7428. Epub 2019 Mar 22. PMID:

30988783; PMCID: PMC6447905.


A11. Tohma YA, Zeyneloglu HB, Aslan OD, Haberal AN, Onalan G, Ayhan A. Prevalence

of endometrial cancer or atypical hyperplasia diagnosed incidentally in

infertility clinic. Am J Obstet Gynecol. 2018 Nov;219(5):503-505. doi:

10.1016/j.ajog.2018.08.008. Epub 2018 Aug 15. PMID: 30118694.


A12. Önalan G, Tohma YA, Zeyneloğlu HB. Effect of Etanercept on the Success of

Assisted Reproductive Technology in Patients with Endometrioma. Gynecol Obstet

Invest. 2018;83(4):358-364. doi: 10.1159/000484895. Epub 2017 Nov 24. PMID:



A13. Zeyneloglu HB, Onalan G. Remedies for recurrent implantation failure. Semin

Reprod Med. 2014 Jul;32(4):297-305. doi: 10.1055/s-0034-1375182. Epub 2014 Jun

11. PMID: 24919029.


A14. Figen Turkcapar A, Seckin B, Onalan G, Ozdener T, Batioglu S. Human

Menopausal Gonadotropin versus Recombinant FSH in Polycystic Ovary Syndrome

Patients Undergoing In Vitro Fertilization. Int J Fertil Steril. 2013

Jan;6(4):238-43. Epub 2013 Mar 3. PMID: 24520446; PMCID: PMC3850313.


A15. Onalan G, Gulumser C, Mulayim B, Dagdeviren A, Zeyneloglu H. Effects of

amifostine on endometriosis, comparison with N-acetyl cysteine, and leuprolide

as a new treatment alternative: a randomized controlled trial. Arch Gynecol

Obstet. 2014 Jan;289(1):193-200. doi: 10.1007/s00404-013-2963-0. Epub 2013 Jul

24. PMID: 23880890.


A16. Yariz KO, Walsh T, Uzak A, Spiliopoulos M, Duman D, Onalan G, King MC, Tekin

M. Inherited mutation of the luteinizing hormone/choriogonadotropin receptor

(LHCGR) in empty follicle syndrome. Fertil Steril. 2011 Aug;96(2):e125-30. doi:

10.1016/j.fertnstert.2011.05.057. Epub 2011 Jun 17. PMID: 21683950; PMCID:



A17. Kıray S, Onalan G, Karabay G, Zeyneloglu H, Kuscu E. Antioxidant prophylaxis

for cellular injury in ovarian surface epithelium resulting from CO?

pneumoperitoneum in a laparoscopic rat model. Arch Gynecol Obstet. 2011

Sep;284(3):765-72. doi: 10.1007/s00404-011-1933-7. Epub 2011 May 27. PMID:



A18. Onalan G, Yilmaz Z, Durak T, Sahin FI, Zeyneloglu HB. Successful pregnancy

with preimplantation genetic diagnosis in a woman with mosaic Turner syndrome.

Fertil Steril. 2011 Apr;95(5):1788.e1-3. doi: 10.1016/j.fertnstert.2010.12.055.

Epub 2011 Jan 26. PMID: 21272868.


A19. Kaya C, Onalan G, Cengiz SD. An increase in systolic blood pressure and

abnormal circadian blood pressure regulation in lean women with polycystic ovary

syndrome. Eur J Obstet Gynecol Reprod Biol. 2010 Jun;150(2):217-8. doi:

10.1016/j.ejogrb.2010.02.018. Epub 2010 Mar 4. PMID: 20206433.


A20. Onalan G, Mulayim B, Toprak T, Baser E, Zeyneloglu HB. Extrauterine

displaced intrauterine devices: when should they be surgically removed? Taiwan J

Obstet Gynecol. 2009 Dec;48(4):415-6. doi: 10.1016/S1028-4559(09)60334-X. PMID:



A21. Tonguc E, Var T, Onalan G, Altinbas S, Tokmak A, Karakaş N, Gulerman C.

Comparison of the effectiveness of single versus double intrauterine

insemination with three different timing regimens. Fertil Steril. 2010

Sep;94(4):1267-1270. doi: 10.1016/j.fertnstert.2009.08.030. Epub 2009 Sep 26.

PMID: 19782353.


A22. Onalan G, Zeyneloglu HB, Bayraktar N. Fenofibrate causes regression of

endometriotic implants: a rat model. Fertil Steril. 2009 Dec;92(6):2100-2. doi:

10.1016/j.fertnstert.2009.05.065. Epub 2009 Jul 5. PMID: 19580963.


A23. Akkaya P, Onalan G, Haberal N, Bayraktar N, Mülayim B, Zeyneloglu HB.

Doxycycline causes regression of endometriotic implants: a rat model. Hum

Reprod. 2009 Aug;24(8):1900-8. doi: 10.1093/humrep/dep106. Epub 2009 Apr 28.

PMID: 19401321.


A24. Mulayim B, Celik NY, Onalan G, Bagis T, Zeyneloglu HB. Sublingual

misoprostol for cervical ripening before diagnostic hysteroscopy in

premenopausal women: a randomized, double blind, placebo-controlled trial.

Fertil Steril. 2010 May 1;93(7):2400-4. doi: 10.1016/j.fertnstert.2009.01.073.

Epub 2009 Feb 24. PMID: 19243750.


A25. Mulayim B, Celik NY, Onalan G, Zeyneloglu HB, Kuscu E. Sublingual

misoprostol after surgical management of early termination of pregnancy. Fertil

Steril. 2009 Aug;92(2):678-81. doi: 10.1016/j.fertnstert.2008.07.1706. Epub 2008

Sep 6. PMID: 18774567.


A26. Pabuccu R, Onalan G, Kaya C, Selam B, Ceyhan T, Ornek T, Kuzudisli E.

Efficiency and pregnancy outcome of serial intrauterine device-guided

hysteroscopic adhesiolysis of intrauterine synechiae. Fertil Steril. 2008

Nov;90(5):1973-7. doi: 10.1016/j.fertnstert.2007.06.074. Epub 2008 Sep 6. PMID:



A27. Onalan R, Onalan G, Tonguc E, Ozdener T, Dogan M, Mollamahmutoglu L. Body

mass index is an independent risk factor for the development of endometrial

polyps in patients undergoing in vitro fertilization. Fertil Steril. 2009

Apr;91(4):1056-60. doi: 10.1016/j.fertnstert.2008.01.002. Epub 2008 Mar 5. PMID:



A28. Pabuccu R, Onalan G, Kaya C. GnRH agonist and antagonist protocols for stage

I-II endometriosis and endometrioma in in vitro fertilization/intracytoplasmic

sperm injection cycles. Fertil Steril. 2007 Oct;88(4):832-9. doi:

10.1016/j.fertnstert.2006.12.046. Epub 2007 Apr 10. PMID: 17428479.


A29. Cincik M, Baykal B, Zeteroglu S, Onalan G, Ceyhan ST, Ergur R. Pronuclear

synchronization and nuclear morphology of mature and in vitro matured oocytes in

the rat: an ultrastructural study. In Vitro Cell Dev Biol Anim. 2005 Sep-

Oct;41(8-9):272-7. doi: 10.1290/0505030R.1. PMID: 16409113.


A30. Onalan R, Onalan G, Gunenc Z, Karabulut E. Combining 2nd-trimester maternal

serum homocysteine levels and uterine artery Doppler for prediction of

preeclampsia and isolated intrauterine growth restriction. Gynecol Obstet

Invest. 2006;61(3):142-8. doi: 10.1159/000090432. Epub 2005 Dec 20. PMID:



A31. Onalan G, Goktolga U, Ceyhan T, Bagis T, Onalan R, Pabuçcu R. Predictive

value of glucose-insulin ratio in PCOS and profile of women who will benefit

from metformin therapy: obese, lean, hyper or normoinsulinemic? Eur J Obstet

Gynecol Reprod Biol. 2005 Dec 1;123(2):204-11. doi:

10.1016/j.ejogrb.2005.05.010. PMID: 16316811.


A32. Pabuccu R, Ceyhan ST, Onalan G, Goktolga U, Ercan CM, Selam B. Successful

treatment of cervical stenosis with hysteroscopic canalization before embryo

transfer in patients undergoing IVF: a case series. J Minim Invasive Gynecol.

2005 Sep-Oct;12(5):436-8. doi: 10.1016/j.jmig.2005.06.003. PMID: 16213431.


A33. Onalan G, Onalan R, Selam B, Akar M, Gunenc Z, Topcuoglu A. Mood scores in

relation to hormone replacement therapies during menopause: a prospective

randomized trial. Tohoku J Exp Med. 2005 Nov;207(3):223-31. doi:

10.1620/tjem.207.223. PMID: 16210834.


A34. Onalan G, Pabuçcu R, Goktolga U, Ceyhan T, Bagis T, Cincik M. Metformin

treatment in patients with polycystic ovary syndrome undergoing in vitro

fertilization: a prospective randomized trial. Fertil Steril. 2005

Sep;84(3):798-801. doi: 10.1016/j.fertnstert.2005.03.043. PMID: 16169430.


A35. Onalan G, Selam B, Onalan R, Ceyhan T, Cincik M, Pabuccu R. Serum and

follicular fluid levels of soluble Fas and soluble Fas ligand in IVF cycles. Eur

J Obstet Gynecol Reprod Biol. 2006 Mar 1;125(1):85-91. doi:

10.1016/j.ejogrb.2005.08.002. Epub 2005 Sep 2. PMID: 16140454.


A36. Onalan G, Selam B, Baran Y, Cincik M, Onalan R, Gündüz U, Ural AU, Pabuccu

R. Serum and follicular fluid levels of soluble Fas, soluble Fas ligand and

apoptosis of luteinized granulosa cells in PCOS patients undergoing IVF. Hum

Reprod. 2005 Sep;20(9):2391-5. doi: 10.1093/humrep/dei068. Epub 2005 Jun 2.

PMID: 15932917.


A37. Günenç MZ, Yesildaglar N, Bingöl B, Onalan G, Tabak S, Gökmen B. The safety

and efficacy of direct trocar insertion with elevation of the rectus sheath

instead of the skin for pneumoperitoneum. Surg Laparosc Endosc Percutan Tech.

2005 Apr;15(2):80-1. doi: 10.1097/01.sle.0000162106.95875.b9. PMID: 15821619.


A38. Pabuccu R, Onalan G, Goktolga U, Kucuk T, Orhon E, Ceyhan T. Aspiration of

ovarian endometriomas before intracytoplasmic sperm injection. Fertil Steril.

2004 Sep;82(3):705-11. doi: 10.1016/j.fertnstert.2004.02.117. PMID: 15374718.


A39. Paşaoğlu H, Bulduk G, Oğüş E, Paşaoğlu A, Onalan G. Nitric oxide, lipid

peroxides, and uric acid levels in pre-eclampsia and eclampsia. Tohoku J Exp

Med. 2004 Feb;202(2):87-92. doi: 10.1620/tjem.202.87. PMID: 14998302.


A40. Onalan G, Pabuçcu R, Onalan R, Ceylaner S, Selam B. Empty follicle syndrome

in two sisters with three cycles: case report. Hum Reprod. 2003

Sep;18(9):1864-7. doi: 10.1093/humrep/deg371. PMID: 12923140.